Incyclix Bio Secures $11.25 Million Series B Extension to Advance the Phase 1/2 Clinical Trial of INX-315 in Patients with CDK4/6 Inhibitor Resistant ER+/HER2- Breast Cancer or CCNE1-Amplified Solid Tumors

RESEARCH TRIANGLE PARK, N.C., Aug. 25, 2025 (GLOBE NEWSWIRE) -- Incyclix Bio, LLC, a next-generation cell cycle control company developing INX-315, a novel, potent and selective CDK2 inhibitor for the treatment of advanced and resistant cancer, today announced it has secured a $11.25 million extension to its Series B financing.

The Series B extension investors include Eshelman Ventures, Eli Lilly and Company, Pharmacosmos and new investor Cape Fear BioCapital. The additional financing will advance Incyclix's ongoing INX-315-01 (NCT05735080), a first-in-human, Phase 1/2 clinical trial of INX-315, a novel, potent and selective CDK2 inhibitor, for the treatment of patients with recurrent advanced/metastatic cancer.

"This additional funding is a validation of the best-in-class potential of INX-315, and we are grateful for the continued support to advance our clinical ...